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From 2007 until 2012, Dr. Parkinson served as President and CEO of Nodality, a biotechnology company focused on the organic characterization of signaling pathways in patients with malignancy to enable more practical therapeutics growth and scientific choice-making. Dr. Parkinson has beforehand led oncology scientific development actions at Novartis ( ), Amgen ( ) and Biogen Idec ( ). He worked on the National Cancer Institute from 1990 to 1997, serving as Chief of the Investigational Drug Branch, after which as Acting Associate Director of the Cancer Therapy Evaluation Program . Dr. Parkinson is a previous Chairman of the Food & Drug Administration Biologics Advisory Committee, has additionally served on the FDA’s Science Board, and is a recipient of the FDA’s Cody Medal.
Based upon the review and discussions described on this report, we recommended to the board of directors that the audited consolidated monetary statements be included in the 2019 Annual Report for filing with the SEC. Although ratification just isn’t required by our bylaws or in any other case, we are submitting the choice to our stockholders for ratification as a matter of good corporate follow and because we worth our stockholders’ views.
In September 2017, Mr. Kirske was appointed as our Chief Financial Officer and commenced full-time employment, along with his annual base wage stage being increased to $350,000 and his goal annual bonus being set at 35% of his base wage Travel Fare Proxies. In February 2019, our compensation committee approved a rise in base salary and bonus opportunity for Mr. Kirske, to $360,500 and 40% of his base salary, respectively.

In February 2018, in connection with our concurrent public offering of frequent inventory, BVF purchased 6.3 million shares of our widespread stock. In addition, BVF exchanged 8.0 million shares of our frequent stock owned by BVF and 575 shares of our Series N Preferred Stock owned by BVF for 12,575 shares of our Series O Preferred Stock, pursuant to the letter agreements mentioned above as well as a further trade agreement executed in February 2018.

This section describes the 2019 compensation we paid to our 2019 named executive officers who’re listed in the “Summary Compensation Table – 2018 and 2019” beneath. We have adopted a Stock Ownership Policy and a Policy Regarding the Recoupment of Certain Compensation Payments (compensation “clawback” coverage), as well as revisions to our Insider Trading Policy to prohibit certain hedging and pledging transactions in our securities by our directors and officers, all as discussed in more detail beneath.

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In the case of any employee of the Corporation or considered one of its Subsidiaries on an approved depart of absence, continued vesting of the award while on leave from the employ of the Corporation or certainly one of its Subsidiaries could also be suspended until the worker returns to service, except the Administrator otherwise offers or applicable law otherwise requires. In no event shall an award be exercised after any applicable maximum term of the award. the authorization by the Administrator of “cashless exercise” procedures with third parties who present financing for the aim of the train of awards according to relevant laws and any limitations imposed by the Administrator. The Administrator might allow awards to be exercised by and paid to, or in any other case transferred to, different persons or entities pursuant to such conditions and procedures, together with limitations on subsequent transfers, because the Administrator could, in its sole discretion, set up in writing.
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If the Annual Meeting is adjourned, discover will be given to our stockholders, if at all, in accordance with our bylaws, the General Corporation Law of the State of Delaware and applicable SEC rules. At the adjourned meeting, we might transact any business which might have been transacted at the authentic assembly. The tackle of our present administrators and executive officers listed is 3101 Western Avenue, Suite 800, Seattle, Washington 98121.
Any permitted transfer shall be subject to compliance with relevant federal, state and foreign securities and change control laws and shall not be for worth (other than nominal consideration, settlement of marital property rights, or for interests in an entity during which more than 50% of the voting interests are held by the Eligible Person or by the Eligible Person’s family members). The Administrator may, however, provide with respect to one or more awards that the truthful market value shall equal the closing price for a share of Common Stock on the Market on the final trading day previous the date in query or the average of the excessive and low buying and selling costs of a share of Common Stock on the Market for the date in query or the most recent buying and selling day. If the Common Stock is now not listed or is not actively traded on the Market as of the applicable date, the honest market worth of the Common Stock shall be the value as fairly decided by the Administrator for functions of the award in the circumstances.

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The Administrator may also provide that deferred settlements include the payment or crediting of interest or different earnings on the deferral quantities, or the payment or crediting of dividend equivalents the place the deferred quantities are denominated in shares. Any Qualified Performance-Based Award or Qualifying Option or SAR (as such terms were defined in Section 5.2 of the prior version of this Plan) granted underneath this Plan previous to November 2, 2017 shall continue to be governed by the phrases of this Plan in effect on the time of grant of such award.
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Using information center proxies to scrape pricing or other knowledge might be tough as one single ban from a web site might render many proxies to turn out to be unusable for a similar function. No modification, suspension or termination of this Plan or modification of any excellent award agreement shall, with out written consent of the participant, have an effect on in any manner materially opposed to the participant any rights or benefits of the participant or obligations of the Corporation beneath any award granted underneath this Plan previous to the effective date of such change. Changes, settlements and other actions contemplated by Section 7 shall not be deemed to represent modifications or amendments for functions of this Section eight.6. Awards payable beneath this Plan shall be payable in shares or from the general belongings of the Corporation, and no special or separate reserve, fund or deposit shall be made to guarantee payment of such awards.
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In March 2020, in connection with our rights offering and separate buy commitments by sure of our traders, BVF purchased a total of three,047 shares of our Series X Preferred Stock, which are convertible into 30.5 million shares of our frequent stock. No shares of Series O Preferred Stock or Series X Preferred Stock owned by BVF have been converted into our frequent stock. In September 2015, we entered into a subscription agreement with BVF pursuant to which we issued 1.zero million shares of our frequent inventory. In addition, we accomplished underwritten public offerings of fifty five,000 shares of our Series N-2 Preferred Stock, no par worth per share in December 2015 and 22,500 shares of our Series N-three Preferred Stock, no par value per share in June 2017.

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The compensation committee has last authority to determine the compensation of our named executive officers. In general, these benefits are meant to attract and retain extremely certified executives. Approximately 65% of Dr. Craig’s target whole direct compensation for 2019 is “at-threat” as described above.
The audit committee can delegate this duty to a number of of its members, offered that such pre-approval choice is presented to the total audit committee and its subsequent scheduled assembly . All providers carried out and associated fees billed by Ernst & Young LLP in the course of the fiscal years offered above had been approved by the audit committee.
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Of the whole combination fees in 2019, less than zero.three% were not accredited by the audit committee pursuant to the de minimis exception offered by Section of Rule 2-01 of Regulation S-X. disposition could apply if the optionee can also be an officer or director of the Company. Any acquire or loss acknowledged on such a untimely disposition of the shares in excess of the amount handled as odd revenue will be characterised as lengthy-time period or short-term capital achieve or loss, relying on the holding period. The U.S. federal revenue tax consequences of the 2017 Plan beneath current federal legislation, which is subject to vary, are summarized in the following dialogue of the final tax ideas applicable to the 2017 Plan. Author Bio




About the Author: Samira is a blogger at brookings.edu, prof-cbd and thebridgebk.

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http://bbc.com/This summary is not meant to be exhaustive and, among other issues, doesn’t describe the deferred compensation provisions of Section 409A of the Internal Revenue Code to the extent an award is subject to and does not satisfy these guidelines, nor does it describe state, native or worldwide tax penalties.
Dr. Parkinson obtained his medical degree from the University of Toronto, has held tutorial positions each at Tufts and on the University of Texas MD Anderson Cancer Center, and has authored over 100 peer-reviewed publications. Mr. Metzger’s business and administration experience in the biopharmaceutical business have been the first skills that led the board of directors to conclude that he should serve on our board of directors. Five of our directors are independent within the that means of the independent director tips of The Nasdaq Stock Market (“Nasdaq”).
  • Consistent with that philosophy, the board of directors has structured the cash and equity award elements of the Director Compensation Policy to offer a complete compensation opportunity for the non-worker administrators that the board believes is cheap.
  • If stockholders approve this proposal, the variety of shares of our common inventory that may be delivered pursuant to awards granted underneath the 2017 Plan shall be increased by a further 5,a hundred,000 shares.
  • There would be a corresponding enhance within the number of shares which may be delivered pursuant to incentive inventory choices granted underneath the 2017 Plan .
  • Our board of administrators is asking you to approve an amendment to our Amended and Restated 2017 Equity Incentive Plan (the “2017 Plan”) to extend the number of shares reserved for issuance thereunder.
  • The sort and terms of awards granted can also change in anyone year or from yr to yr based mostly on any variety of variables, including, without limitation, modifications in rivals’ compensation practices or changes in compensation practices usually, and the need to attract, retain and incentivize key expertise.

Dr. Parkinson’s enterprise and management experience in the biopharmaceutical and healthcare industry, in addition to his experience at the FDA, have been the first qualifications that led the board of administrators to conclude that he should serve on our board of administrators. Dr. Parkinson has served as a enterprise associate at New Enterprise Associates , Inc. since 2012 and in 2016 moved to the position of venture advisor to NEA.

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To help ensure that the administrators and officers maintain sufficient management over the timing of their transactions in our securities, we prohibit our directors and officers from margining any of our securities in a margin account or otherwise pledging any of our securities as collateral for a loan. We prohibit all of our administrators, officers and staff from participating in any hedging or monetization transaction that may allow them to realize from or offset any decrease in the market worth Generate Leads for Sales Teams of our securities. The compensation committee believes that each named govt officer’s bonus alternatives had been applicable bearing in mind the efficiency that might be required to earn these quantities. The 2019 annual base salaries paid to our named executive officers are set forth in the “Summary Compensation Table – 2018 and 2019” under. The main components of our executive compensation program include base salaries, annual money incentives and fairness incentives.
The letter does not have a specified time period and offers for Mr. Seeley to obtain an initial annualized base wage of $375,000. Mr. Seeley is eligible to receive an annual discretionary bonus, with a goal bonus of 30% of base wage and a maximum bonus of 75% of base wage, and to participate in our profit packages. In September 2017, Mr. Seeley’s annual base salary level was increased to $410,000 in connection with his appointment as our Chief Operating Officer, and his goal annual bonus was elevated to forty% of base wage, efficient for 2018. In February 2019, our compensation committee approved an increase in base wage for Mr. Seeley, to $422,300.
If stockholders don’t approve this proposal, these grants is not going to be efficient, and we will be unable to grant the fairness incentives we believe are essential to supply retention incentives. Subject to certain exceptions contained within the 2017 Plan, awards underneath the 2017 Plan generally aren’t transferable by the recipient aside from by will or the laws of descent and distribution and are usually exercisable, through the recipient’s lifetime, only by the recipient. Any quantities payable or shares issuable pursuant to an award generally might be paid only to the recipient or the recipient’s beneficiary or legal representative. This does not take into account the 5,one hundred,000 shares that may be added to the 2017 Plan if stockholders approve this proposal or the 5,104,000 shares subject to options which might be contingent on stockholder approval of this proposal. Please see the dialogue beneath underneath “Specific Benefits under the 2017 Plan” and “Aggregate Past Grants Under the 2017 Plan” for detailed data on sure awards that we granted which might be contingent on stockholder approval of this 2017 Plan proposal in addition to past awards granted under the Plans.
The following table sets forth data regarding compensation for fiscal years 2018 and 2019 for services rendered by our named govt officers. We keep govt well being packages for the advantage of the named government officers, and these executives are also entitled to take part in our profit programs that are available to all of our staff, including our 401 and employee inventory buy plan. The compensation committee also considers the suggestions of our Chief Executive Officer with respect to the compensation for each govt aside from himself. Our compensation committee doesn’t assign a specific weight to those components and none of those elements by itself will compel a selected compensation decision.
As of December 31, 2019 and 2018, BVF beneficially owned approximately 12.zero% of our excellent widespread stock. Matthew D. Perry, a member of our Board, is the President of BVF and portfolio manager for the underlying funds managed by the firm. The foregoing “Summary Compensation Table” must be learn at the side of the tables and narrative descriptions that follow. The “Outstanding Equity Awards at Fiscal 2019 Year-End” desk supplies additional information on the named government officers’ potential realizable value with respect to their equity awards. The “Potential Payments upon Termination or Change in Control” section provides info on the benefits the named govt officers may be entitled to obtain in connection with sure terminations of their employment and/or a change in management.
Nothing on this Section 8.3, however, is intended to adversely have an effect on any categorical independent right of such person beneath a separate employment or service contract apart from an award agreement. In any of the occasions referred to in this Section 7.2, the Administrator could take such motion contemplated by this Section 7.2 prior to such occasion to the extent that the Administrator deems the action needed to allow the participant to realize the benefits intended to be conveyed with respect to the underlying shares. Without limiting the generality of the foregoing, the Administrator may deem an acceleration and/or termination to happen immediately prior to the applicable event and, in such circumstances, will reinstate the unique terms of the award if an occasion giving rise to an acceleration and/or termination does not happen. Without limiting the previous paragraph, in connection with any event referred to within the previous paragraph or any change in control event outlined in any relevant award agreement, the Administrator may, in its discretion, provide for the accelerated vesting of any award or awards as and to the extent decided by the Administrator in the circumstances.


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For these functions, “goal complete direct compensation” refers to Dr. Craig’s base wage, target bonus opportunity and fairness-based awards granted through the fiscal 12 months . RESOLVED, that the compensation paid to our named executive officers, as disclosed on this proxy assertion pursuant to the SEC’s govt compensation disclosure guidelines , is hereby approved.
No participant, beneficiary or other person shall have any proper, title or interest in any fund or in any particular asset of the Corporation or considered one of its Subsidiaries by purpose of any award hereunder. Neither the provisions of this Plan , nor the creation or adoption of this Plan, nor any motion taken pursuant to the provisions of this Plan shall create, or be construed to create, a belief of any type or a fiduciary relationship between the Corporation or one of its Subsidiaries and any participant, beneficiary or different particular person. To the extent that a participant, beneficiary or different particular person acquires a proper to receive payment pursuant to any award hereunder, such right shall be no greater than the proper of any unsecured basic creditor of the Corporation.
Our board of directors believes that the processes it has established for overseeing risk could be efficient beneath a variety of management frameworks and subsequently don’t materially have an effect on its choice of management structure as described beneath “Leadership Structure” above. Independent directors meet in regularly scheduled classes with out management. One of our administrators in workplace on the time of our 2019 Annual Meeting attended such meeting. Mr. Perry’s administration consulting experience and his expertise investing in biotechnology companies have been the first qualifications that led the board of directors to conclude that he should serve on our board of administrators.

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If stockholders fail to ratify the choice, the audit committee will reconsider whether or not to retain that firm. Even if the selection is ratified, the audit committee in its discretion could direct the appointment of a unique impartial registered public accounting agency at any time through the 12 months if the audit committee feels that such a change would be in our and our stockholders’ best interests. The Administrator has accredited sure awards beneath the 2017 Plan which are contingent on stockholder approval of this proposal.
Our certificate of incorporation and bylaws present that the variety of our administrators shall be between 5 and 12 persons and shall be mounted by decision of our board of administrators. outstanding on the document date will be entitled to one vote per share on all issues to be voted upon on the Annual Meeting. As of the close of business on the record date, there were 73,681,593 shares of our widespread stock issued and excellent. Paid providers like our Indian proxy server utilise numerous strategies, together with HTTPS between proxies and goal servers, to make sure customer security. Also, these rotating residential proxies only support the whitelisted IPs authentication mechanism and you may’t whitelist more than 1 IP no matter your subscription plan.
Stockholder approval of the modification won’t, by itself, trigger any change in our capital accounts. However, any future issuance of further shares of frequent stock approved pursuant to this proposal would in the end result in dilution of existing stockholders’ equity interests. subject to stockholder approval of Proposal 3 and have an train value equal to $1 per share. These choices will vest in accordance with the vesting terms relevant to different annual choice grants made pursuant to our Director Compensation Policy. The amounts reported in the “Fees Earned or Paid in Cash” column replicate the quantities earned with respect to fiscal yr 2019 for the director’s retainer and charges for chairing and/or serving on relevant board committees.
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Payment of awards may be in the form of money, Common Stock, different awards or combinations thereof because the Administrator shall determine, and with such restrictions as it might impose. The Administrator may require or permit participants to elect to defer the issuance of shares or the settlement of awards in money under such rules and procedures as it could set up under this Plan.


BVF purchased 30,000 shares of our Series N-2 Preferred Stock and 6,750 shares of our Series N-three Preferred Stock in such choices. BVF transformed 30,000 shares of our Series N-2 Preferred Stock and 6,a hundred seventy five shares of our Series N-3 Preferred Stock into approximately 2.7 million shares and 4.1 million shares of our common stock, respectively.
In accordance with existing audit committee policy and the requirements of the Sarbanes-Oxley Act, all services to be provided by Ernst & Young LLP are subject to pre-approval by the audit committee or certainly one of its members to whom such authority could from time to time be delegated. This consists of audit services, audit-associated providers, tax services and different services. Such pre-approval relates to a particular category or group of providers and is subject to a particular budget. The Sarbanes-Oxley Act prohibits an issuer from obtaining sure non-audit services from its auditing agency so as to avoid certain potential conflicts of interest; we have not in recent times obtained any of those companies from Ernst & Young LLP, and we are in a position to acquire such providers from different service providers at competitive charges. Pursuant to the charter for the audit committee, the audit committee pre-approves all auditing companies and permissible non-audit services to be carried out by our unbiased registered public accounting agency and the related charges.

We have adopted a procedure referred to as “householding,” which the SEC has accredited. Under this procedure, stockholders of report who have the same tackle and final name will receive only one copy of our proxy materials except we receive opposite directions from a number of of such stockholders. Upon oral or written request, we will deliver promptly a separate copy of the proxy supplies to a stockholder at a shared handle to which a single copy of proxy materials was delivered. If you’re a beneficial stockholder, please contact your bank, broker, trustee or different nominee immediately if you have questions, require additional copies of the proxy materials, want to obtain multiple reports by revoking your consent to householding or wish to request single copies of the proxy materials in the future.
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